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As there are many causes of adrenal fatigue, micronutrients can be very beneficial. The most common trigger of adrenal fatigue is stress, which leads to an increase in nutrient consumption, especially of magnesium, zinc, vitamin C and pantothenic acid.
A lack of nutrients impairs cell metabolism and can disrupt the function of the adrenal glands. As is the case with many chronic diseases, adrenal fatigue also involves disorders of mitochondrial function and cell metabolism. Therefore, the nutrients that regulate the function of the mitochondria and protect the cells from oxidative damage play a major role. These are coenzyme Q10, vitamin C, vitamin E, glutathione, selenium and magnesium.
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Certain B vitamins can help regenerate the adrenal gland. Pantothenic acid, significantly influences the formation of adrenal hormones, essential for the healthy functioning of the adrenal glands.
For best effect, take in combination with magnesium, vitamin C and vitamin E. The entire vitamin B complex is required for optimal hormone production in the adrenal glands. In addition to pantothenic acid niacin and vitamin B6 are required for proper hormone function They also activate cytokines, that control the immune response, and inhibit NF-κB, which triggers inflammation.
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Long-term stress leads to a lack of nutrients and oxidative stress from free radicals, as the antioxidants needed to combat them are deficient. Free radicals in large quantities lead to the development of many diseases, such as Alzheimer's, cardiovascular diseases and cancer. Therefore, antioxidants such as glutathione, vitamin C, coenzyme Q10 and vitamin E are of fundamental importance.
Glutathione, which is composed of the amino acids cysteine, glutamine and glycine, is present in almost all body cells and is one of the most important antioxidants. It has a strengthening effect on the immune system, detoxifies the body and regenerates other antioxidants. It inhibits NF-κB and is involved in the induction of inducible nitric oxide synthase.
Vitamin C is important for the immune system and is significantly involved in the functioning of the adrenal glands. As it is needed for the production of all hormones, this is also where the highest concentration of vitamin C in the body is found. In states of stress, increased levels of stress hormones such as cortisol are produced. Large quantities of vitamin C are needed for their production. If a vitamin C deficiency occurs, the adrenal gland reacts by further increasing the production of cortisol, which leads to an even higher vitamin C consumption. Coenzyme Q10 is used to produce ATP in the respiratory chain and counteracts oxidative stress.
Nitrosative stress also plays a major role as reactive nitrogen species such as nitric oxide and peroxin nitrite can induce apoptosis. In addition, reactive nitrogen species can trigger a variety of inflammatory, neurological, cardiovascular and metabolic diseases. The antioxidant vitamin E, the peroxin nitrite scavenger selenium and zinc, which is involved in the protonation of superoxide anions to hydrogen peroxide, show a protective effect. An adequate intake of antioxidants is therefore of great importance.
Also important is the intake of L-carnitine, which supports energy metabolism through the transport of fatty acids into the mitochondria.
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