| Dietary sources | |
| Wine leaves denotes the vine leaves of the “Noble vine“ (Vitis vinifera subsp. vinifera), also called “Genuine vine“. Its use as a medicinal plant dates back to the Greek physician Galenos. Grape vine leaves can also be found in the diet. For example, he Turkish-Greek “Dolma“ are, roulades of stuffed vine leaves. In France, certain cheeses are wrapped in vine leaves. |
| Wine leaves in venous diseases |
| Wine leaves contain important bioactive polyphenols. These flavonoids, proanthocyanidins and anthocyanins, which are responsible for the color of the plant, are also used therapeutically for their antioxidant properties. The effect of the vine leaf extract in venous diseases is based on the sealing of endothelial clefts in the vascular walls so that the outflow of plasma and water into the tissue is prevented. In addition, the extract protects the venous endothelial cells from damaging inflammatory mediators and improves microcirculation in the vessels (1). Clinical studies have shown an improvement in blood flow and oxygen supply to the tissues and a reduction in leg swelling (2). There is also an anti-inflammatory, analgesic and antipyretic effect (3). |
| Effect | Indication | Dosage |
| Physiological effects at a low intake |
Preventive at first signs of connective tissue weakness and varicose changes (pain and heaviness in the legs, nocturnal calf cramps, itching, swelling of the legs) | 200 - 800 mg/d |
| Complementary therapy for chronic venous disease, chronic venous insufficiency and diabetic foot | 200 - 800 mg/d | |
| For hemorrhoids & varices | 200 - 800 mg/d |
| General mode of administration | |
| When |
Red wine leaf extract should be taken with meals. |
| Side effects | |
| There are no known side effects to date. | |
| Contraindications | |
| No contraindications are known to date. | |
| Drug or nutrient interactions | |
| None | No relevant interactions are known to date. |
| References |
|
(1) Wagner Hildebert, Wiesenauer Markus: Phytotherapie. Phytopharmaka und pflanzliche Homöopathika. 2003 |
