Cat's Claw

Synonym(s): quinic acid, Uncaria tomentosa
Nutrient group: plant extracts & active ingredients

Sources and physiological effects

Dietary sources
Cat's claw (Uncaria tomentosa) belongs to the Rubiaceae family and is native to the the South American rainforest. Root extracts obtained from this vine have long been used in herbal medicine due to their positive effect on the immune system. 
Physiological effects
Antioxidant
  • Protects cells from oxidative damage
  • Reduction of lipid peroxidation

Detailed information

Cat’s Claw – a Peruvian phytotherapeutic to increase immunological performance
Cat’s Claw is a vine whose root extract is traditionally used in South American herbal medicine for chronic inflammations, infections, tumors and gastric ulcers. Despite numerous studies, the mechanism of their proven effecicacy is still unclear(1). Recent studies identify quinic acid as one of the primary active substances. Quinic acid prevents the growth of genetically modified cells without inducing premature cell death. This gives the immune system improved possibilities for DNA repair and thus stimulates the entire immune system, inhibits inflammatory processes and improves protection against tumors (2). Strong antioxidant properties of Cat's Claw extract caused by oligomeric procyanidins and phenolic acids have also been demonstrated. They protect the lipids in the biological membranes of the immune cells from peroxidation (3).

Indications

Effect Indication Dosage
Physiological effects
at a low intake
Preventive at times of increased infection risk 100 – 200 mg/d
Complementary therapy for weakened immune defense 400 – 500 mg/d
Complementary therapy for tumor diseases 400 – 500 mg/d

Administration

General mode of administration
 
When
 
Cat’s-Claw extract should be taken between meals.
Side effects
No side effects are known to date.
Contraindications
No contrainidcations are known to date.

Interactions

Drug interactions 
None No interactions are known to date.
Nutrient interactions
None No interactions are known to date.

References

References

1) Wagner, H., Wiesenauer, M. 2003. Phytotherapie. Phytopharmaka und pflanzliche Homöopathika.

2) Berhard Watzl, Claus Leitzmann. 1999. Bioaktive Substanzen in Lebensmitteln.

3) Sheng, Y. et al. 2005. An active ingredient of Cat's Claw water extracts. Journal of Ethnopharmacology 96, Nr. 3: 577–584. doi:10.1016/j.jep.2004.10.002.


References Interactions:

Stargrove, M. B. et al. Herb, Nutrient and Drug Interactions: Clinical Implications and Therapeutic Strategies, 1. Auflage. St. Louis, Missouri: Elsevier Health Sciences, 2008.

Gröber, U. Mikronährstoffe: Metabolic Tuning –Prävention –Therapie, 3. Auflage. Stuttgart: WVG Wissenschaftliche Verlagsgesellschaft Stuttgart, 2011.

Gröber, U. Arzneimittel und Mikronährstoffe: Medikationsorientierte Supplementierung, 3. aktualisierte und erweiterte Auflage. Stuttgart: WVG Wissenschaftliche Verlagsgesellschaft Stuttgart, 2014.

 

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